Hematolymphoid Neoplasms of Breast – A Case Series with Review of Lymphoid Cell Rich Lesions of Breast

Objective: Hematolymphoid neoplasms involving breast (HLNB) are rare with majority of lesions in being epithelial nature. There no characteristic clinical and radiologic features to distinguish carcinomas from HLNB. However, it is essential recognise lesion as hematolymphoid nature for appropriate patient management. This case series highlights clinical, radiologic, pathologic HLNB breast.
 Methods: Clinical data (age, sex, laterality, site size tumor, interval secondary involvement, stage, treatment follow up), patients over a period 6 years (2014-20) were recorded. Pathologic differential diagnosis lymphoid cell rich also discussed.
 Results: Six cases identified during this period. constitutes 0.22 % malignancies breast, 0.4% non-Hodgkin lymphoma (NHL), 1.2% extra nodal NHL one each myeloid sarcoma plasmacytoma.
 Conclusion: extremely histologically mimics numerous other entities, which may be misdiagnosed without immunohistochemical evaluation. Thus, critical pathologist aware the diagnostic pitfalls avoid misinterpretation.